At the European Society for Medical Oncology (ESMO) Congress this week, investigators presented data for a new and potentially important drug, ribociclib (Novartis). This oral medication is ...

Recent Progress Anticipated Upcoming Milestones Present updated Phase 2 data showing palazestrant in combination with ribociclib at the San Antonio ... nuclear receptors, and mechanisms of acquired ...

A drug commonly used to treat breast cancer might be able to help people living with hereditary hemorrhagic telangiectasia ...

The team found adding ribociclib, a drug that belongs to a class of CDK4/6 inhibitors, to standard hormone therapy not only ...

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack—blocking the energy supply T cells depend on. The work ...

Inhibition of CDK6 may prevent arteriovenous malformations in hereditary hemorrhagic telangiectasia by regulating endothelial ...

Medically reviewed by Marla Anderson, MDCancer is as old as humanity, and the history of breast cancer is a fantastic example ...

I fell in love with cable driven mechanisms a few years ago and put together some of my first mechanical tentacles to celebrate. But only after playing with them did I start to understand the ...

Defense mechanisms are rooted in Freud’s theory of personality.According to his model, the mind has three dueling forces: the id (unconscious and primitive urges for food, comfort, and sex), the ...

Palbociclib, Ribociclib and Abemaciclib are FDA-approved CDK4/6 inhibitors ... Dr. Yoshida's laboratory are currently working on dissecting the molecular mechanisms of both intrinsic and acquired ...

A mechanism is a set of moving parts that work together to make something happen. A slider is a kind of mechanism that has a bar or rod that moves forwards and backwards, or side to side ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...