Ribociclib belongs to a class of medications called kinase inhibitors; it inhibits the cyclin-dependent kinase (CDK) 4 and 6. It is used for treating hormone receptor (HR)-positive, human ...

Novartis NVS announced that the Committee for Medicinal Products for Human Use (“CHMP”) of the European Medicines Agency (EMA ...

A drug commonly used to treat breast cancer might be able to help people living with hereditary hemorrhagic telangiectasia ...

NICE has recommended moving Novartis’ Kisqali (ribociclib) from interim funding ... NICE recommended Kiskali be taken out of the Cancer Drugs Fund, which has been providing interim reimbursement ...

In May 2024, Google DeepMind released AlphaFold 3, a game changing protein folding model that predicts with 50% better ...

The recent update on the palazestrant + ribociclib combination in treating ER+/HER2- metastatic ... With an Investigational New Drug (IND) filing for OP-3136 expected soon and a Phase 1 study planned, ...

Palazestrant has been granted U.S. Food and Drug Administration (FDA ... and in Phase 1/2 combination studies with CDK4/6 inhibitors (palbociclib and ribociclib), a PI3Ka inhibitor (alpelisib), and an ...

The ribociclib population is more broad ... So those are very exciting drugs. T-DXd and Enhertu have both have been used in ER-positive, HER2-negative [HER2–] metastatic breast cancer.

Drugs such as Novo Nordisk’s blockbuster Ozempic can cut drug and alcohol abuse by up to 50% according to a new study, adding to mounting evidence that the drugs yield health benefits beyond ...

One of the most prominent medical developments in recent years has been the emergence of a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). The best known of these ...

Revenue: Revenue was $0 for the third quarter of 2024, as compared to $25.2 million for the third quarter of 2023. The decrease was primarily due to the recognition of previously received milestone ...

Researchers used drugs Palbociclib and Ribociclib, which are known to block the CDK6 protein in multiplying cancer cells and found that it stopped the abnormal cell growth in animal models with ...